Pharmaceutical Analysis: Importance & Methods
August 16, 2018

The pharmaceutical analysis is something that is now done using a variety of advanced tools, instruments, and software, but many of the pharmaceutical analysis techniques used in chemical analysis and monitoring have been around for a long time. The basic ideas behind many of these applications have remained almost the same, although the equipment used has become much more sophisticated, for example, gravimetry and titration.

Analytical techniques in pharmaceutical analysis

The chemical analysis of the chemical properties of materials has allowed many advances in all branches of science, in medicine and pharmaceutical products and the development of consumer goods.

Gravimetry studies

Gravimetry instrumental analysis samples to determine the amount of analyte present by measuring the weight, this attribute being measured before and after a process that causes a physical change in the sample, for example, evaporation by heat. Titration is another older method of chemical analysis that is performed with samples of an analyte in a solution to which a reactive substance is added. The test is continued until an equivalence point is reached, for example, in the acid-based titration with a pH indicator.

Mass spectrometry

Other forms of chemical analysis and layout are relatively modern innovations, which have been possible with the introduction of new technologies and instruments that allow these methodologies. One of these analytical techniques is mass spectrometry. It is a systematic method that determines the properties of an analyte using magnetic or electric fields to measure the mass/charge ratio of molecules. There are several methods of instrumental analysis that use mass spectrometry, which differs in the type of ionization produced.


Microscopy is another instrumental analysis that is becoming an increasingly important component of the analytical process, as microscopes have become increasingly sophisticated and powerful. Visual examination of molecules, particles and individual cells in biological samples have become an instrumental part of analytical chemistry and instrumental analysis procedures, both alone and in conjunction with other analytical methods.


Spectroscopy is a pharmaceutical analysis technique employed to determine the properties of analytes in a sample based on a measurement of the interactions of the analyte with electromagnetic radiation. There is a wide variety of spectroscopic techniques, the distinction between them is the part of the spectrum occupied by the radiation used. Some spectroscopic methods and instruments use X-rays, infrared light, ultraviolet light, visible, ultraviolet light and many others, and some are particularly suitable for different chemical analysis applications.


Other pharmaceutical technologies and techniques used in trace analysis and other forms of analytical chemistry include crystallography, a qualitative analysis method that analyzes the diffraction patterns produced by the interaction of the analyte with X-rays method is similar to spectroscopy. Thermal analysis separation techniques including electrophoresis and chromatography and various electroanalytical methods can also be used, depending on the type of sample analyzed and the requirements of the analytical process.


Chemical analysis in general and trace analysis, in particular, have allowed astronomers and astrophysicists to learn more not only about our world but about the rest of our solar system and has been the key to discovering planets in other parts of our galaxy. Advances in analytical chemistry have shaped the world we live in today, and the influence of these technologies will be incalculable for the future of the human race.